A FEMALE DOG PROGRESSIVELY GROWING FATIGU E AND HOARSE

A female dog (Collie dog, eight years of age, non-spayed) was referred to the University Clinic for Companion Animals with signs and symptom s suggesting endogenous progesterone induced acromegaly and cystic end ometrial hyperplasia. The dog had glucose intolerance, but the growth hormone concentration in plasma was within the reference range. The la tter was probably due to the decline of progesterone at the end of the luteal phase, resulting in an abrogation of the process of progestero ne-induced growth hormone hypersecretion. After ovariohysterectomy the glucose-tolerance normalized.