SEQUENTIAL DEVELOPMENT OF 2 CONNECTIVE-TISSUE DISEASES IN JUVENILE PATIENTS

The sequential development of two connective tissue diseases in the sa me patient has been rarely reported. We describe 2 juvenile patients, a 15-year-old girl who, after having juvenile rheumatoid arthritis (JR A) for a 7-year period presented with clearly defined features of syst emic lupus erythematosus with diffuse proliferative glomerulonephritis . The 2nd case, a 9-year-old boy developed erosive polyarticular JRA a fter having had a clear,picture of dermatomyositis in infancy. In both cases there was a lengthy disease free period between the 2 diseases. 1