COOCCURRENCE OF COLLAGENOUS COLITIS WITH SERONEGATIVE SPONDYLOARTHROPATHY - REPORT OF A CASE AND LITERATURE-REVIEW

Collagenous colitis is an uncommon cause of chronic watery diarrhea, c haracterized by colonic deposition of collagen. Nonerosive, oligoartic ular, peripheral arthritis has previously been noted in about 7% of pa tients with collagenous colitis. We describe a patient with collagenou s colitis who concurrently developed erosive, seronegative spondyloart hropathy affecting peripheral and axial joints. Synovial histology was characterized by a conspicuous inflammatory infiltrate comprised of h istiocytes, lymphocytes and plasma cells. Collagenous colitis is sugge sted to be a systemic autoimmune disorder, with extraintestinal featur es such as thyroiditis and arthritis.