THE MYCOBACTERIUM-BOVIS 32-KILODALTON PROTEIN ANTIGEN INDUCES HUMAN CYTOTOXIC T-CELL RESPONSES

Authors
MUNK ME DEBRUYN J GRAS H KAUFMANN SHE
Citation
Me. Munk et al., THE MYCOBACTERIUM-BOVIS 32-KILODALTON PROTEIN ANTIGEN INDUCES HUMAN CYTOTOXIC T-CELL RESPONSES, Infection and immunity, 62(2), 1994, pp. 726-728
Citations number
24
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
62
Issue
2
Year of publication
1994
Pages
726 - 728
Database
ISI
SICI code
0019-9567(1994)62:2<726:TM3PAI>2.0.ZU;2-N
Abstract
The 30-kDa protein (P32) is a mycobacterial secreted antigen which is homologous in Mycobacterium bovis and M. tuberculosis. In vitro, P32 i nduced T-cell proliferation. M. tuberculosis- or P32-stimulated T-cell lines lysed macrophages pulsed with P32 or M. tuberculosis, respectiv ely. We conclude that P32 stimulates cytotoxic T cells specifically.