A NOVEL-APPROACH TO THE ASYMMETRIC-SYNTHESIS OF MANZAMINE-A - CONSTRUCTION OF THE TETRACYCLIC ABCE RING-SYSTEM

Authors
MARTIN SF LIAO YS WONG YL REIN T
Citation
Sf. Martin et al., A NOVEL-APPROACH TO THE ASYMMETRIC-SYNTHESIS OF MANZAMINE-A - CONSTRUCTION OF THE TETRACYCLIC ABCE RING-SYSTEM, Tetrahedron letters, 35(5), 1994, pp. 691-694
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
5
Year of publication
1994
Pages
691 - 694
Database
ISI
SICI code
0040-4039(1994)35:5<691:ANTTAO>2.0.ZU;2-M
Abstract
The enantiomerically pure tetracyclic ABCE subunit of manzamine A has been constructed by an intramolecular Diels-Alder reaction of the viny logous imide 13 to give the ABC tricyclic core 14; elaboration of 14 i nto 16 followed by a novel olefin metathesis reaction to form the azoc ine ring then delivered the tetracycle 17.