DISPIROKETALS IN SYNTHESIS .6. HIGHLY STEREOSELECTIVE ALKYLATION AF DISPIROKETAL PROTECTED LACTATE AND GLYCOLATE ENOLATES

Authors
DOWNHAM R KIM KS LEY SV WOODS M
Citation
R. Downham et al., DISPIROKETALS IN SYNTHESIS .6. HIGHLY STEREOSELECTIVE ALKYLATION AF DISPIROKETAL PROTECTED LACTATE AND GLYCOLATE ENOLATES, Tetrahedron letters, 35(5), 1994, pp. 769-772
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
5
Year of publication
1994
Pages
769 - 772
Database
ISI
SICI code
0040-4039(1994)35:5<769:DIS.HS>2.0.ZU;2-W
Abstract
Protected lactic acid enolates have been alkylated with a range of ele ctrophiles to give the substituted adducts with moderate to excellent stereoselectivity. A chiral protected glycolic acid adduct has also be en doubly alkylated with high stereoselectivity.