LIPID PROFILE IN THE CHINESE OLD-OLD - COMPARISON WITH YOUNGER AGE-GROUPS AND RELATIONSHIP WITH SOME CARDIOVASCULAR RISK-FACTORS AND PRESENCE OF DISEASES

Citation
J. Woo et al., LIPID PROFILE IN THE CHINESE OLD-OLD - COMPARISON WITH YOUNGER AGE-GROUPS AND RELATIONSHIP WITH SOME CARDIOVASCULAR RISK-FACTORS AND PRESENCE OF DISEASES, Cardiology, 83(5-6), 1993, pp. 407-414
Citations number
16
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
ISSN journal
00086312
Volume
83
Issue
5-6
Year of publication
1993
Pages
407 - 414
Database
ISI
SICI code
0008-6312(1993)83:5-6<407:LPITCO>2.0.ZU;2-8
Abstract
In a health survey of 2,032 elderly Hong Kong Chinese aged 70 years an d over selected by stratified random sampling, a subset of 199 subject s (96 M, 103 F) were selected for a study of their lipid profile. No a ge and sex differences were observed in mean total cholesterol (TC), h igh-density lipoprotein cholesterol (HDL-C), low-density lipoprotein c holesterol (LDL-C), and triglyceride concentrations in this subgroup. Compared with values from younger Chinese subjects from a previous sur vey, TC and LDL-C showed an age-related rise up till about 60 years, f ollowed by a gradual decline. HDL-C concentrations showed little varia tion with age. Nonagenarians had a LDL/HDL ratio similar to subjects i n the < 24 age group and lower than male subjects in the age 35-64 age group. HDL-C was lower in those with heart disease or hypertension. O ther lipid parameters were not influenced by the presence of other chr onic diseases, self-perceived health status, or cognitive impairment. TC was positively associated with the Barthel Index, a measure of func tional ability. Positive associations between obesity indices and dias tolic blood pressure, and TC, LDL-C, and triglycerides were present. N egative associations were found for HDL-C. These findings are suggesti ve of a trend towards a more favourable lipid profile in extreme old a ge, which does not appear to be accounted for by the increasing preval ence of chronic diseases in old age giving rise to low cholesterol con centrations. The association of lipids with other cardiovascular risk factors is still demonstrable in this age group.