PS2 AND RESPONSE TO ADJUVANT HORMONE-THERAPY IN PRIMARY BREAST-CANCER

Authors
SPYRATOS F ANDRIEU C HACENE K CHAMBON P RIO MC
Citation
F. Spyratos et al., PS2 AND RESPONSE TO ADJUVANT HORMONE-THERAPY IN PRIMARY BREAST-CANCER, British Journal of Cancer, 69(2), 1994, pp. 394-397
Citations number
26
Categorie Soggetti
Oncology
Journal title
British Journal of Cancer → ACNP
ISSN journal
00070920
Volume
69
Issue
2
Year of publication
1994
Pages
394 - 397
Database
ISI
SICI code
0007-0920(1994)69:2<394:PARTAH>2.0.ZU;2-K
Abstract
We reviewed 319 primary breast tumours for cytosolic pS2 content, with a median follow-up of 6 years. pS2 status correlated positively with oestradiol and progesterone receptors and negatively;with Scarff, Bloo m and Richardson grade. pS2 positivity was associated with longer over all survival, particularly in patients who received hormone therapy, i n whom pS2 status was also predictive of the response to therapy.