Ve. Orel et al., CHANGES IN MECHANOCHEMIEMISSION OF LYMPHOCYTES FROM TUMOR-BEARING ANIMALS AFTER EXPOSURE TO IONIZING-RADIATION, Eksperimental'naa onkologia, 18(4), 1996, pp. 345-348
Electric component of electromagnetic mechanochemiemission (MCE) initi
ated by springy mechanic energy at various stages of cellular cycle of
peripheral blood lymphocytes (PBL) in rats with Guerin's carcinoma as
well as after gamma-radiation in vitro with doses of 0.25 and 1.0 Gy
has been examined. Periodograms of mean spectral power density of MCE
PBL in tumor-bearer rats at G(0)-phase had different maximal peaks in
comparison with analogous parameters of cells in intact animals. Effec
t of ionizing irradiation initiated peculiarities of kinetic parameter
s of MCE PBL in both animals with Guerin's carcinoma and in intact ani
mals, lower correlative dependence of changes of time rows of MCE PBL
in rats with tumors without radiation and after radiation with dose of
0.25 Gy in comparison with identic indices of MCE of intact animals c
ells has been registered, at the same time, higher dose of irradiation
- 1.0 Gy had an opposite effect. It is suggested that MCE kinetics fr
om the surface of PBL reflects changes of mechanochemiemission process
es in signals of management of cell genes expression.