CHANGES IN MECHANOCHEMIEMISSION OF LYMPHOCYTES FROM TUMOR-BEARING ANIMALS AFTER EXPOSURE TO IONIZING-RADIATION

Citation
Ve. Orel et al., CHANGES IN MECHANOCHEMIEMISSION OF LYMPHOCYTES FROM TUMOR-BEARING ANIMALS AFTER EXPOSURE TO IONIZING-RADIATION, Eksperimental'naa onkologia, 18(4), 1996, pp. 345-348
Citations number
16
Categorie Soggetti
Oncology
Journal title
ISSN journal
02043564
Volume
18
Issue
4
Year of publication
1996
Pages
345 - 348
Database
ISI
SICI code
0204-3564(1996)18:4<345:CIMOLF>2.0.ZU;2-S
Abstract
Electric component of electromagnetic mechanochemiemission (MCE) initi ated by springy mechanic energy at various stages of cellular cycle of peripheral blood lymphocytes (PBL) in rats with Guerin's carcinoma as well as after gamma-radiation in vitro with doses of 0.25 and 1.0 Gy has been examined. Periodograms of mean spectral power density of MCE PBL in tumor-bearer rats at G(0)-phase had different maximal peaks in comparison with analogous parameters of cells in intact animals. Effec t of ionizing irradiation initiated peculiarities of kinetic parameter s of MCE PBL in both animals with Guerin's carcinoma and in intact ani mals, lower correlative dependence of changes of time rows of MCE PBL in rats with tumors without radiation and after radiation with dose of 0.25 Gy in comparison with identic indices of MCE of intact animals c ells has been registered, at the same time, higher dose of irradiation - 1.0 Gy had an opposite effect. It is suggested that MCE kinetics fr om the surface of PBL reflects changes of mechanochemiemission process es in signals of management of cell genes expression.