The reasons for high prevalence of neoplastic process have been invest
igated on the basis of case records of 320 patients with histologicall
y verified vulvar cancer: among them inopportune taking medical advice
, non-timely diagnosis of malignant processes, and tactical mistakes o
f the treatment were indicated. It was proposed a new instrument (toot
hed vulvar knife) for picking out cytological material which helps to
raise accuracy and obtain improved cytological diagnosis of vulvar pre
cancer.