A CONVENIENT SYNTHESIS OF 2-PYRAZOLINES AND PYRAZOLES FROM ALDEHYDE HYDRAZONES AND ETHYL PROPIOLATE

Authors
KAMITORI Y HOJO M MASUDA R FUJISHIRO M WADA M
Citation
Y. Kamitori et al., A CONVENIENT SYNTHESIS OF 2-PYRAZOLINES AND PYRAZOLES FROM ALDEHYDE HYDRAZONES AND ETHYL PROPIOLATE, Heterocycles, 38(1), 1994, pp. 21-25
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
38
Issue
1
Year of publication
1994
Pages
21 - 25
Database
ISI
SICI code
0385-5414(1994)38:1<21:ACSO2A>2.0.ZU;2-2
Abstract
Aldehyde methylhydrazones (3) reacted with ethyl propiolate in the pre sence of acetic acid affording 4-ethoxycarbonyl-1-methyl-2-pyrazolines (4) in 13 - 44% yields. Easily 4 was dehydrated to the corresponding pyrazoles (6) by treatment with H2O2 in the presence of FeCl2.