PREPARATION OF ANTI-PYRENYL ANTIBODY AND ITS CHIRAL RECOGNITION AGAINST A NONNATURAL AMINO-ACID CARRYING PYRENYL GROUP

Authors
IMAIZUMI M SISIDO M
Citation
M. Imaizumi et M. Sisido, PREPARATION OF ANTI-PYRENYL ANTIBODY AND ITS CHIRAL RECOGNITION AGAINST A NONNATURAL AMINO-ACID CARRYING PYRENYL GROUP, Chemistry Letters, (1), 1994, pp. 51-52
Citations number
5
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
1
Year of publication
1994
Pages
51 - 52
Database
ISI
SICI code
0366-7022(1994):1<51:POAAAI>2.0.ZU;2-H
Abstract
Monoclonal antibody was raised against a tetrapeptide containing L-pyr enylalanine. The antibody bound the tetrapeptide as well as L-pyrenyla lanine methyl ester, indicating that it recognizes the pyrenyl group. The antibody, however, did not bind D-pyrenylalanine methyl ester. Thi s finding suggests a potentiality of monoclonal antibodies for chiral separations.