ENANTIOSELECTIVE ALDOLATION MEDIATED BY FUNCTIONALIZED BILAYER-MEMBRANES AS ARTIFICIAL VITAMIN-B(6)-DEPENDENT ENZYMES

Authors
MURAKAMI Y KIKUCHI J MIYAJIMA T HISAEDA Y
Citation
Y. Murakami et al., ENANTIOSELECTIVE ALDOLATION MEDIATED BY FUNCTIONALIZED BILAYER-MEMBRANES AS ARTIFICIAL VITAMIN-B(6)-DEPENDENT ENZYMES, Chemistry Letters, (1), 1994, pp. 55-58
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
1
Year of publication
1994
Pages
55 - 58
Database
ISI
SICI code
0366-7022(1994):1<55:EAMBFB>2.0.ZU;2-U
Abstract
Supramolecular bilayer assemblies, each composed of a peptide lipid ha ving an (S)-alanine residue, an additional one having (S)-binaphthol a nd (S)-alanine moieties, a hydrophobic pyridoxal derivative, and coppe r(II) ions, mediated the aldolation of glycine with benzaldehyde to af ford beta-phenylserine under mild reaction conditions, exhibiting mark ed enantioselectivity.