Gd. Cascino et Mr. Trenerry, SIGNIFICANCE OF POSTOPERATIVE ELECTROENCEPHALOGRAMS IN PATIENTS WITH EXTRATEMPORAL LESIONAL EPILEPSY, Journal of epilepsy, 7(1), 1994, pp. 2-6
We retrospectively studied EEGs performed 1 week, 3 months, and 1 year
after surgery (lesionectomy or lesion resection with corticectomy) in
24 patients with extratemporal lesional epilepsy who had a mean durat
ion of follow-up of 2.5 years. All patients had intractable partial se
izures and underwent a comprehensive presurgical evaluation including
long-term EEG monitoring. Twenty of the 24 patients had interictal epi
leptiform activity (IEA) identified on the preoperative sleep and awak
e EEG recordings. The presence of IEA 1 year after surgery was associa
ted with recurrent seizure activity (p < 0.05). The postoperative EEG
recordings, however, revealed no IEA in the two patients with persiste
nt seizures who had no epileptiform abnormality on the preoperative st
udy. The extent of cortical resection appeared to have no significant
effect on the recording of IEA after surgery. One-year postoperative E
EG recordings are prognostically useful in patients with extratemporal
lesional epilepsy who undergo surgical treatment.