Dy. Lee et al., EFFECT OF TIBIAL LENGTHENING ON THE GASTROCNEMIUS-MUSCLE - A HISTOPATHOLOGIC AND MORPHOMETRIC STUDY IN RABBITS, Acta orthopaedica Scandinavica, 64(6), 1993, pp. 688-692
We observed the changes of the gastrocnemius muscle in relation to the
percentage of lengthening of the rabbit's tibia by callotasis. 75 rab
bits were separated into 3 lengthening groups, 10, 20, and 30 percent
lengthening, respectively. Histopathologic observations, based on the
fiber size variation, internalization of the nuclei, degeneration, reg
eneration, and endomysial fibrosis of muscle fibers, revealed that sub
stantial changes occurred in the latter groups. Histomorphometrically,
the decrease in the mean size of Types I and II muscle fibers was obs
erved in all lengthening groups, but there was no significant change i
n the proportion of the muscle fiber types in any of the lengthening g
roups.