SYNOVIAL-FLUID TRANSFUSION WITH AND WITHOUT CORTICOSTEROID IN INDUCEDARTHRITIC BUFFALO CALVES - CHANGES IN SYNOVIAL-FLUID

Aseptic arthritis of knee joint was induced in 18 buffalo calves by in tra-articular injection of turpentine oil. Animals were divided in gro ups A, B and C. Synovial fluid was collected before induction of arthr itis and subsequently on days 7, 15 and 30. Group A served as control and no treatment was given. In group B, treatment with autologous syno vial fluid transfusion was carried out on seventh post-induction day. In group C transfusion was supplemented with corticosteroid. Significa nt decrease in relative viscosity, mucin precipitate quality, glucose concentration and significant increase in total leucocyte count, total proteins, acid and alkaline phosphatase activities were observed at a ll stages in control group. As compared to control group, there was si gnificant increase in relative viscosity, mucin precipitate quality, g lucose concentration and significant decrease in total leucocyte count , total proteins and enzyme activities in both the treatment groups. A lthough many of these parameters remained significantly altered as com pared to base value at the end of experiment in group B, they did not differ significantly in group C.