A 79-year-old male was admitted to the hospital with the complaint of
bloody sputum. Chest X-rav revealed an abnormal shadow in the right up
per lobe. Macroscopically, the lesion measured about 3.5x2.5x2.0 cm wi
th a central cavity containing pus. Histologically, the lesion was com
posed of interlacing fibroblastic proliferation with abundant plasma c
ell infiltration and central cavitation. The inner surface of the cavi
ty wall was partially covered by bronchial epithelial cells; there was
no cartilage found, suggesting that the lesion had developed from chr
onic inflammatory processes in relation to ectatic bronchioles. Since
the pathogenesis of plasma cell granuloma (PCG) has not been well esta
blished, it is probable that this case represents one stage in the dev
elopment of classic PCG.