ALGORITHM FOR THE ASSESSMENT OF PEAK PURITY IN LIQUID-CHROMATOGRAPHY WITH PHOTODIODE-ARRAY DETECTION

Authors
SANCHEZ FC KHOTS MS MASSART DL DEBEER JO
Citation
Fc. Sanchez et al., ALGORITHM FOR THE ASSESSMENT OF PEAK PURITY IN LIQUID-CHROMATOGRAPHY WITH PHOTODIODE-ARRAY DETECTION, Analytica chimica acta, 285(1-2), 1994, pp. 181-192
Citations number
21
Categorie Soggetti
Chemistry Analytical
Journal title
Analytica chimica acta → ACNP
ISSN journal
00032670
Volume
285
Issue
1-2
Year of publication
1994
Pages
181 - 192
Database
ISI
SICI code
0003-2670(1994)285:1-2<181:AFTAOP>2.0.ZU;2-K
Abstract
An algorithm for peak purity analysis based on the Gram-Schmidt orthog onalization method is described. The data are pretreated by using two different normalization techniques. The performance of this approach i s investigated for liquid chromatography with photodiode-array detecti on (LC-DAD) data. The results are compared with the ones obtained by m eans of fixed size window evolving factor analysis (FSW EFA). The effe cts of heteroscedasticity and non linearities are discussed.