Fifty-eight children with syncope were evaluated prospectively to dete
rmine the characteristics of syncope in the pediatric age group and th
e yield of various diagnostic tests. The age at first syncope ranged f
rom 0.5 to 15 years. Twenty-five children presented after a single epi
sode and 33 after multiple episodes. Ten had a history of breath-holdi
ng spells. Nineteen had a family history of syncope. A diagnosis was e
stablished in 53 patients (91%): vasodepressor (31), cardioinhibitory
(13), tussive (3), hyperventilation (2), and mixed syncope (4). In fiv
e patients (9%), the cause remained unknown. The diagnosis was establi
shed from the history in 45 cases, by a positive oculocardiac reflex i
n 11, and by the head-up tilt test in four. We conclude that the cause
of most cases of pediatric syncope is vasodepressor or cardioinhibito
ry and can be diagnosed by good history-taking. Costly evaluations are
rarely necessary.