SCALING IN BIOCHEMICAL KINETICS - DISSECTION OF A RELAXATION-OSCILLATOR

In a case study of a class of biochemical models, methods of scaling a re employed to determine the expected limits of validity of singular p erturbation approaches to a relaxation oscillator. This work complemen ts earlier analysis of the use of the quasi-steady-state approximation for the Michaelis-Menten approximation. These studies present an adva ntage over more conventional approaches in which attention is concentr ated on a single parameter, in that the range of convergence is deline ated more precisely in the full parameter space of the problem.