A REVIEW OF TREATMENT OF DUODENAL AND GASTRIC-ULCERS PANTOPRAZOLE VS OMEPRAZOLE

Authors
SCHEPP W REHNER M WITZEL L
Citation
W. Schepp et al., A REVIEW OF TREATMENT OF DUODENAL AND GASTRIC-ULCERS PANTOPRAZOLE VS OMEPRAZOLE, Alimentary pharmacology & therapeutics, 8, 1994, pp. 53-57
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Alimentary pharmacology & therapeutics → ACNP
ISSN journal
02692813
Volume
8
Year of publication
1994
Supplement
1
Pages
53 - 57
Database
ISI
SICI code
0269-2813(1994)8:<53:AROTOD>2.0.ZU;2-#
Abstract
The efficacy and safety of pantoprazole in the treatment of duodenal a nd gastric ulcers has been compared with that of the first proton pump inhibitor omeprazole in two (previously reported) clinical studies. P antoprazole (40 mg/day) administered orally was an effective and well- tolerated treatment for both indications. Pantoprazole was as effectiv e as omeprazole (20 mg/day) and had a similar safety profile. For gast ric ulcers, the healing rate with pantoprazole was superior to that wi th omeprazole at 4 weeks.