Td. Myles et al., PREGNANCY AFTER TREATMENT OF EPITHELIOID HEMANGIOENDOTHELIOMA - A CASE-REPORT, Journal of reproductive medicine, 39(1), 1994, pp. 52-54
Pregnancy occurred in a woman who had undergone hepatic, cerebral and
myocardial resection of epithelioid hemangioendotheliomas (EHEs). The
overall course of her pregnancy did not seem to be affected by the pri
or EHEs, though the pregnancy tons complicated by pvc term delivery. T
he patient was observed to have elevated maternal serum alpha-fetoprot
ein (MSAFP); a complete workup found no abnormalities in the fetus, an
d a relationship between the EHEs and elevated MSAFP was not appal ent
. Because of the unknown contribution of EHE to MSAFP, inclusion of ta
rgeted (level II) ultrasound and possibly amniocentesis seem appropria
te to prenatally diagnose structural anomalies and ensure a normal kar
yotype.