Dural sinus thrombosis is a rare, potentially fatal complication of a
radical neck dissection. The prognosis can vary from complete recovery
to rapid death. Magnetic resonance venography provides an effective,
noninvasive diagnosis. The goals of therapy are to decrease intracrani
al pressure and to lyse the thrombus. Systemic anticoagulation and sys
temic thrombolytics are controversial therapies. The direct intrasinus
infusion of thrombolytic agents is under investigation.