PITUITARY CARCINOMA

Citation
Md. Cusimano et al., PITUITARY CARCINOMA, Skull base surgery, 4(1), 1994, pp. 46-51
Citations number
41
Categorie Soggetti
Neurosciences,Surgery
Journal title
ISSN journal
10521453
Volume
4
Issue
1
Year of publication
1994
Pages
46 - 51
Database
ISI
SICI code
1052-1453(1994)4:1<46:PC>2.0.ZU;2-T
Abstract
The presence of distant metastases may be asymptomatic in patients who present with symptoms and signs due to the local mass effects of an i nvasive pituitary adenoma. A case of pituitary carcinoma in a 54-year- old man who presented with widespread asymptomatic distant metastases 12 years after initial diagnosis is reviewed. The long course and asym ptomatic metastases suggested a relatively slow-growing malignancy. Th e factors that played a role in the pathogenesis of the metastasis are unknown. A review of the litera on pituitary carcinoma suggests that accurate diagnosis and a multidisciplinary approach to management of s uch lesions emphasizing surgery, radiotherapy, and hormonal manipulati on may provide these patients with the longest and best quality of sur vival.