Am. Warren et Jm. Crampton, MARINER - ITS PROSPECTS AS A DNA VECTOR FOR THE GENETIC MANIPULATION OF MEDICALLY IMPORTANT INSECTS, Parasitology today, 10(2), 1994, pp. 58-63
Originally described in Drosophila mauritiana, the mariner transposabl
e element has very recently been identified in 63 other insect species
, representing ten insect orders, and including the malaria-vector mos
quito, Anopheles gambiae. Ann Warren and Julian Crampton here discuss
how transposable elements can be exploited as valuable research tools
for the molecular characterization of genomes and as DNA vectors for g
enome manipulation and the 'creation' of transgenic organisms.