HLA ANTIGENS IN ARAB CHILDREN WITH STEROID-RESPONSIVE NEPHROTIC SYNDROME

Authors
ZAKI M DAOUD AS ALSALEH QA ALNAJEDI AK WHITE AG
Citation
M. Zaki et al., HLA ANTIGENS IN ARAB CHILDREN WITH STEROID-RESPONSIVE NEPHROTIC SYNDROME, Pediatric nephrology, 8(1), 1994, pp. 74-75
Citations number
NO
Categorie Soggetti
Pediatrics,"Urology & Nephrology
Journal title
Pediatric nephrology
ISSN journal
0931041X → ACNP
Volume
8
Issue
1
Year of publication
1994
Pages
74 - 75
Database
ISI
SICI code
0931-041X(1994)8:1<74:HAIACW>2.0.ZU;2-H
Abstract
Forty-eight Arab patients with steroid-responsive childhood nephrotic syndrome were studied for the frequency of HLA-A, -B, -C and -DR antig ens. HLA-DR7 was significantly increased in the patient group (63% vs. 28%, P = 0.0002) confirming reports of a DR7 association in other eth nic groups and indicating a universal association with this antigen. H LA-CW6 was also significantly increased (44% vs. 21%, P corr. = 0.042) . HLA-DQW1 was significantly reduced in the patients (29% vs. 57%, P c orr. = 0.012) as was HLA-CW4 (6% vs. 24%, P corr. = 0.042).