Simple metal salts such as lithium perchlorate and zinc triflate effec
tively promote aldol condensation between silyl enol ethers and aldehy
des or acetals in non-protic solvents to yield the O-protected aldols
in good yields. A slight preference for the syn aldol is observed when
a prochiral silyl enol ether reacts with benzaldehyde, a complete syn
stereoselectivity being obtained only in the case of the hindered sil
yl enol ether 14. The method appears to be simple and competitive with
other ones previously described.