SYNTHESIS OF SPHINGOSINE RELATIVES .14. A NEW SYNTHESIS OF SYMBIORAMIDE, A CA-ATPASE ACTIVATOR FROM SYMBIODINIUM SP(+)

Authors
MORI K UENISHI K
Citation
K. Mori et K. Uenishi, SYNTHESIS OF SPHINGOSINE RELATIVES .14. A NEW SYNTHESIS OF SYMBIORAMIDE, A CA-ATPASE ACTIVATOR FROM SYMBIODINIUM SP(+), Liebigs Annalen der Chemie, (1), 1994, pp. 41-48
Citations number
16
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
1
Year of publication
1994
Pages
41 - 48
Database
ISI
SICI code
0170-2041(1994):1<41:SOSR.A>2.0.ZU;2-V
Abstract
Symbioramide [(2S,2'R,3R,3'E)-N-(2'-hydroxy-3'-octadecenoyl) dihydrosp hingosine, 1] was synthesized from D-erythrodihydrosphingosine (19) an d R,E)-2'-tert-butyldimethylsilyloxy-3'-octadecenoic acid (14), which was prepared from (E)-2-octadecen-1-ol (4) by employing the Sharpless asymmetric epoxidation. The (2S,2'S,3R,3'E)-isomer 28 of 1 was also sy nthesized to further confirm the structure of 1.