Myositis due to the etiologic agent of Lyme disease, Borrelia burgdorf
eri, has been reported nine times in the English-language literature;
there has been but a single report of exacerbation of dermatomyositis
due to B. burgdorferi in a patient with known dermatomyositis. Multipl
e infectious agents, but not B. burgdorferi, have been hypothesized to
trigger dermatomyositis. We report the first case of dermatomyositis
that appears to have been triggered by B. Burgdorferi. This case invol
ved an individual from Westchester County, NY, who presented with skin
lesions suggestive of erythema migrans and who was seropositive for L
yme disease. He soon developed a clinical syndrome suggestive of derma
tomyositis: periorbital edema, dysphagia, proximal muscle weakness, an
d a markedly elevated level of creatine phosphokinase. We also review
the clinical presentation and response to treatment of patients with L
yme myositis.