DERMATOMYOSITIS ASSOCIATED WITH LYME-DISEASE - CASE-REPORT AND REVIEWOF LYME MYOSITIS

Citation
Hw. Horowitz et al., DERMATOMYOSITIS ASSOCIATED WITH LYME-DISEASE - CASE-REPORT AND REVIEWOF LYME MYOSITIS, Clinical infectious diseases, 18(2), 1994, pp. 166-171
Citations number
19
Categorie Soggetti
Microbiology,Immunology
ISSN journal
10584838
Volume
18
Issue
2
Year of publication
1994
Pages
166 - 171
Database
ISI
SICI code
1058-4838(1994)18:2<166:DAWL-C>2.0.ZU;2-Y
Abstract
Myositis due to the etiologic agent of Lyme disease, Borrelia burgdorf eri, has been reported nine times in the English-language literature; there has been but a single report of exacerbation of dermatomyositis due to B. burgdorferi in a patient with known dermatomyositis. Multipl e infectious agents, but not B. burgdorferi, have been hypothesized to trigger dermatomyositis. We report the first case of dermatomyositis that appears to have been triggered by B. Burgdorferi. This case invol ved an individual from Westchester County, NY, who presented with skin lesions suggestive of erythema migrans and who was seropositive for L yme disease. He soon developed a clinical syndrome suggestive of derma tomyositis: periorbital edema, dysphagia, proximal muscle weakness, an d a markedly elevated level of creatine phosphokinase. We also review the clinical presentation and response to treatment of patients with L yme myositis.