DENGUE INFECTION COMPLICATED BY SEVERE HEMORRHAGE AND VERTICAL TRANSMISSION IN A PARTURIENT WOMAN

A Thai woman with a febrile illness was delivered of a healthy infant by cesarean section. The etiology of her 2-day fever was unknown at th e time of surgery; results of serology performed later established a d iagnosis of dengue infection. Postoperative hemostatic monitoring was not performed. She experienced massive and prolonged (8 days) wound he morrhage that necessitated multiple transfusions of blood, platelets, and frozen plasma. The newborn became febrile on his 6th day of life. Dengue virus type 2 was isolated from his serum. Although the infant d eveloped marked thrombocytopenia, his illness was brief and uncomplica ted. This report emphasizes the hazards of surgical intervention in pa tients with acute dengue infection. We also believe it to be the first report of vertical transmission of dengue in humans.