Lj. Scherer et al., COMPARATIVE-ANALYSIS OF THE SEQUENCE AND STRUCTURE OF 2 DROSOPHILA-MELANOGASTER GENES ENCODING VITELLINE MEMBRANE-PROTEINS, Gene, 136(1-2), 1993, pp. 121-127
Two Drosophila melanogaster vitelline membrane protein-encoding genes
(VM), located at polytene band positions 26A and 34C, have been cloned
and comparatively characterized at the nucleotide level. Sequence ana
lysis of genomic and cDNA clones for the two genes, VM26A.1 and VM34C.
1, indicates that both are similarly organized with a central highly c
onserved domain [Scherer et al., Dev. Biol. 130 (1988) 786-788] which
is flanked by unrelated regions, and that both genes lack introns. Com
parison of the upstream regions reveals that both VM genes contain a h
eptameric element identical to one associated with the D. melanogaster
yolk protein-encoding genes (YP). This heptamer occurs in the specifi
c 5' flanking region responsible for ovarian temporal- and tissue-spec
ific control in both VM and YP genes. A putative chorion transcription
factor 2 site is also associated with an upstream control element of
VM26A.1, but not with any sequenced portion of VM34C.1.