Pm. White et al., THE ROLE OF COMPUTED TOMOGRAPHIC EXAMINATION OF THE PELVIS IN THE MANAGEMENT OF TESTICULAR GERM-CELL TUMORS, Clinical Radiology, 52(2), 1997, pp. 124-129
Aim: To clarify the role of pelvic CT in the imaging of patients with
germ cell testicular tumours (GCPT). Patients and methods: A retrospec
tive analysis was undertaken of all CT examinations performed on patie
nts with GCTT at a regional oncological centre over a 3-year-period, P
atient notes were reviewed and data on histology, tumour marker levels
, therapy and clinical course obtained. The review interpretation,vas
combined with the original radiological report and clinical data to ar
rive at a consensus result. Results: Four hundred and forty-three exam
inations on 167 patients were included. One hundred and nineteen exami
nations (27%) demonstrated abdominal and/or pelvic lymph node enlargem
ent. Modal metastasis was entirely or predominantly ipsilateral in 73/
77 examinations from left-sided primary tumours (95%) and 35/42 examin
ations from right-sided tumours (83%). Pelvic nodal enlargement was id
entified in 37 examinations from 16 patients, Thirteen of these sixtee
n patients possessed an identifiable risk factor for pelvic nodal meta
stasis; the remaining three had unequivocal nodal metastases in the ab
domen, Combined abdominopelvic CT increased the effective dose equival
ent (EDF) by 2.6 mSv (74%) compared with abdominal examination alone.
Three hundred pelvic CT examinations were performed on 117 patients wi
thout risk factors for pelvic nodal metastasis. For this cohort tile r
adiation burden from pelvic CT was 0.78 manSv, giving a risk of induct
ion of a single fatal cancer of 3.9%. Conclusion: We advocate pelvic C
T only at the time of staging, except in patients with a risk factor f
or pelvic nodal metastasis. Any unequivocal abdominal lymph node enlar
gement should be regarded as a risk factor, Implementation of this pol
icy would safely reduce pelvic CT examinations in patients with testic
ular rumours by nearly 50%, with a consequent reduction in patient rad
iation exposures and a resource saving.