THE RELATIONSHIP BETWEEN ERYTHROCYTE SUPEROXIDE-DISMUTASE ACTIVITY AND PLASMA-LEVELS OF SOME TRACE-ELEMENTS (AL, CU, ZN) OF DIALYSIS PATIENTS

Authors
HASANOGLU E ALTAN N SINDEL S ONGUN CO BALI M ALTINTAS E
Citation
E. Hasanoglu et al., THE RELATIONSHIP BETWEEN ERYTHROCYTE SUPEROXIDE-DISMUTASE ACTIVITY AND PLASMA-LEVELS OF SOME TRACE-ELEMENTS (AL, CU, ZN) OF DIALYSIS PATIENTS, General pharmacology, 25(1), 1994, pp. 107-110
Citations number
32
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
General pharmacology → ACNP
ISSN journal
03063623
Volume
25
Issue
1
Year of publication
1994
Pages
107 - 110
Database
ISI
SICI code
0306-3623(1994)25:1<107:TRBESA>2.0.ZU;2-K
Abstract
1. The effect of erythropoietin and some trace elements on superoxide dismutase (SOD) activity of dialysis patients have been studied. 2. SO D activity of dialysis patients was found to be decreased. 3. The effe ct of erythropoietin on SOD activity was not found in vitro. 4. Plasma and erythrocyte aluminum increased in dialysis patients, but no signi ficant change in plasma copper was found. 5. Plasma zinc levels of dia lysis patients were found to be decreased. 6. These results suggest th at inhibition of erythrocyte SOD activity of dialysis patients may con tribute to their anemia.