Cortical bone mass was quantified in 1278 Nigerian children (695 males
and 583 females) aged 3-16 years in a prospectively designed cross-se
ctional and longitudinal study. The total bone width (T) and medullary
cavity width (M) were measured at the midshaft of the second metacarp
al bone using a direct reading caliper. From the above measurements th
e cortical width (C), cortical area (CA), and percent cortical area (P
CA) were calculated using the method of Garn et al. [6] and showed a p
rogressive increase of T, C, CA and PCA, reaching a plateau at 15 year
s. At all ages, the values for both T and M are higher in males than i
n females. On the other hand, and contrary to established normal value
s amongst both white and black Americans, between the ages of 9 and 15
the female values for C are higher than those for males. This differe
nce is greatest at the age of 12 years (p < 0.001). The implication of
this finding may be that during these years, African male children do
not compensate for the increased endosteal resorption with a greater
total cortical width (T), since the medullary width in females remains
relatively constant over the years.