BEHAVIOR OF NUCLEOLAR ORGANIZER REGIONS IN THE DIFFERENT WISTAR RAT-LIVER LOBES

The area and number of silver-nucleolar organizer regions (Ag-NORs) in the hepatic lobes were determined in 3 male Wistar rats. There was a statistically significant increase in the percentage of Ag-NORs per nu cleus in the right lateral and caudate lobe in relation to the left la teral and middle lobes. The area and number of Ag-NORs are greater in the caudate and right lateral lobes in relation to the left lateral an d middle lobes. Since the Ag-NOR is a parameter which indicates hepato cytic protein synthesis, the different activity which corresponds to e ach lobe of the rat's liver makes it possible to assume that there is a functional heterogeneity which should be considered in the study of the hepatic regeneration according to the type of partial hepatectomy carried out.