Citation
J. Quetinleclercq et al., 2,7-DIHYDROXYAPOGEISSOSCHIZINE FROM ROOT BARK OF STRYCHNOS-GOSSWEILERI, Phytochemistry, 35(2), 1994, pp. 533-536
Citations number
24
Categorie Soggetti
Plant Sciences
Journal title
ISSN journal
00319422
Volume
35
Issue
2
Year of publication
1994
Pages
533 - 536
Database
ISI
SICI code
0031-9422(1994)35:2<533:2FRBOS>2.0.ZU;2-J
Abstract
In this paper, we describe the isolation and structural determination
of 2,7-dihydroxyapogeissoschizine, a new alkaloid from the root bark o
f Strychnos gossweileri. Elucidation of its structure is based mainly
on 1D and 2D NMR studies; its conformation was optimized by energy min
imization. According to a preliminary test, this substance shows low t
oxicity to B16 melanoma cells, but not for non-cancer 3T3 fibroblasts
cultured in vitro.