A report is given on first experiences with motor cortex stimulation i
n 10 patients with different forms of neuropathic pain. Three of them
had central pain as sequelae of cerebrovascular disease. In none of th
em did the stimulation provide pain relief. Two patients had pain from
peripheral nerve injuries. One did not respond, but the other obtaine
d about 50% pain relief. The remaining 5 patients with trigeminal neur
opathy experienced definite pain relief varying between 60 and 90%. Du
ring test stimulation most patients had one or two short-lasting gener
alized seizures. But no one had any motor effects after permanent impl
antation. Motor cortex stimulation appears to be a new and promising p
ossibility of pain treatment, especially in cases with trigeminal neur
opathy, but many problems have yet to be solved, before a clear indica
tion could be given.