SURVEY OF THE PHENOMENOLOGY AND PHARMACOTHERAPY OF COMPULSIVE AND IMPULSIVE-AGGRESSIVE SYMPTOMS IN PRADER-WILLI-SYNDROME

Prader-Willi Syndrome (PWS) is a congenital disorder characterized by hyperphagia as well as by other behavioral disturbances such as self-m utilation and temper outbursts. Some of these symptoms have been repor ted to respond to psychotropic medications. A systematic survey was co nducted to gather information on the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in PWS. Both compulsi ve and impulsive-aggressive symptoms are frequent in this population. Pharmacotherapeutic intervention may have a role in the management of these symptoms. Rigorous diagnostic and treatment studies should be un dertaken in this population.