MONOCLONAL CYTOPLASMIC IMMUNOGLOBULIN AND PATHOMORPHOLOGICAL REACTIONS IN LYMPH-NODES IN SPONTANEOUS BOVINE LEUKEMIA-VIRUS INFECTION

Authors
LEVKUT M PLANK L LEVKUTOVA M KONRAD V
Citation
M. Levkut et al., MONOCLONAL CYTOPLASMIC IMMUNOGLOBULIN AND PATHOMORPHOLOGICAL REACTIONS IN LYMPH-NODES IN SPONTANEOUS BOVINE LEUKEMIA-VIRUS INFECTION, Veterinary immunology and immunopathology, 40(2), 1994, pp. 163-170
Citations number
16
Categorie Soggetti
Immunology,"Veterinary Sciences
Journal title
Veterinary immunology and immunopathology → ACNP
ISSN journal
01652427
Volume
40
Issue
2
Year of publication
1994
Pages
163 - 170
Database
ISI
SICI code
0165-2427(1994)40:2<163:MCIAPR>2.0.ZU;2-H
Abstract
Prescapular lymph nodes from 109 cows seropositive to bovine leukemia virus (BLV) were examined for the presence of light chains of bovine i mmunoglobulin (Ig) kappa or lambda. A variety of reactions were presen t in prescapular lymph nodes, including B-zonal hyperplasia (23 cases, 21.1%), T-zonal hyperplasia (52 cases, 47.7%), mixed hyperplasia (18 cases, 16.5%), pulp proliferation (six cases, 5.5%), and atrophy (ten cases, 9.2%). In the case of pulp proliferation the immunohistological examination identified only Ig of a single light chain type lambda. T he possible relationship of a monoclonal expression of Ig and developm ent of tumorous proliferation is discussed in the study.