Objective: To compare the identifiable pulmonary abnormalities on preo
perative chest radiographs and CT scans with the histologic findings i
n patients requiring surgical intervention for recurrent or persistent
pneumothoraces. Materials and methods: Chest radiographs were reviewe
d retrospectively in 116 consecutive patients (aged 16 to 81 years) wh
o had undergone thoracotomy for recurrent or persistent pneumothorax.
CT scans were performed in 21 patients. Chest radiographs and CT scans
were reviewed by two observers without knowledge of the histologic fi
ndings, All specimens were reviewed by a surgical pathologist. Results
: Seventy-nine (68%) patients had parenchymal abnormalities and five (
4%) had pleural thickening evident on the radiograph, The most common
radiographic abnormalities included apical bullae (n=51), apical scarr
ing (n=17), and diffuse emphysema (n=9). Twenty of 21 (95%) CT scans d
emonstrated either a parenchymal or a pleural abnormality. CT demonstr
ated emphysema in four patients with normal radiographs, as well as ad
ditional findings in six patients with abnormal radiographs, Histologi
cally, 74 patients had focal irregular emphysema, 26 had distal acinar
emphysema, six had mixed emphysema, four had isolated bullae or blebs
, two had mesothelioma, and one each had the following: metastatic ang
iosarcoma, subpleural fibrosis, congenital cystic adenomatoid malforma
tion, and tuberculous pleuritis with inactive interstitial fibrosis an
d honeycombing. Conclusion: Most patients with surgically treated pneu
mothorax have emphysema or an isolated bulla, Although these findings
may not be apparent on the radiograph and seen on CT, this probably do
es not affect patient management, In most cases of pneumothorax relate
d to other causes, findings consistent with the diagnosis can be seen
on the radiograph.