Job exposure matrices (JEM) are designed to link information on occupa
tion with information on exposure to specific workplace hazards. in sp
ite of some [imitations, JEM are particularly useful in large retrospe
ctive epidemiological studies. The development of JEM designed for a c
ompany or an industrial sector have a more specific field of applicati
on than JEM used in population-based studies, and can therefore be bas
ed on a more detailed classification of occupations and better exposur
e information. This article reviews on-going research related to the d
esign of JEM in support of industry-based studies. The review covers d
esign aspects related to the structure of JEM, and specially the four
main axes that may produce differences on exposure characteristics: ag
ent (exposure), job, time and place. Attention has also been given to
the different sources of information on exposure, the characteristics
of the exposure and the validation of exposure estimates.