Jg. Kayanakis et al., PHYSICAL-TRAINING OF PATIENTS WITH CHRONI C CONGESTIVE-HEART-FAILURE - IMMEDIATE AND MEDIUM-TERM EFFECTS, La Presse medicale, 23(3), 1994, pp. 121-126
Objectives: While physical training is known to improve cardiac perfor
mance in patients with chronic congestive heart failure, we conducted
this study to evaluate the effect of such training programmes. Methods
: The study group included 48 untrained patients with stable chronic h
eart failure controled with the same daily oral regimen including 0.25
mg digitoxin, 40 mg furosemide and 50 mg captopril. Halt of the patie
nts (n = 24) entered a physical rehabilitation programme for a 3 week
period. Each daily session included passi- ve mobilization of the limb
s (10 min), respiratory exercises (10 min) and endurance exercise on a
n ergometric cycle with a maximum work load of 50, 60 and 70 % of the
theoretical maximal load for weeks 1, 2 and 3 respectively. The other
24 patients did not change their physical activity level and served as
controls. The immediate and medium term effects (3 months after the e
nd of the training programme) were assessed using exercise tests, left
ventricular isotopic ejection fraction and plethysmography of the low
er limbs. The quality of life was compared using the NYHA functio- nal
classification and the Goldsman questionnaire. Results: At the end of
the 3-week training period, and compared with the control group, ther
e was a moderate improvement of VO2max (p < 0.02) and a 10 % improveme
nt in the ejection frac- tion (p < 0.05) in the trained patients. Ther
e was a clearly signifi- cant improvement in the anaerobic threshold a
nd arterial blood now rate (p < 0.001) and lowered vascular resistance
(p < 0.001) and venous tone (p < 0.001). The quality of life was also
improved in the training group. However, 3 weeks after the end of the
training period, these differences disappeared. Conclusion: Patients
with chronic heart failure can benefit from physical training showing
functional improvement and no delete- rious effect on left ventricular
function. This beneficial effect is nonetheless temporary and would a
ppear to be due to improved skeletal muscle oxidative capacity and per
ipheral haemodynamics.