Rationale and Objectives. The authors investigated the diagnostic effi
cacy of compression of real-time ultrasound (US) examinations. Methods
. Low- and high-compression recordings (9:1 and 15:1, respectively) of
examinations were generated by using Joint Photographic Experts Group
algorithms. Seven radiologists used a five-level response scale to an
swer questions about the presence, number, and location of focal fibro
id tumors in 67 randomly sorted uterine examinations. The images were
viewed after no, low, and high compression. Results were evaluated by
using multipatient, multireader receiver operating characteristic jack
knife analysis. Results. Given the reduction in the US digital video r
ates from 74 Mbit/ sec for uncompressed images to 8 Mbit/sec for low c
ompression and 4.7 Mbit/sec for high compression, there were no statis
tically significant differences in accuracy between the compression sc
hemes. Confidence intervals suggested that the sample size was adequat
e. Conclusion. Compressed images with compression ratios of 9:1 and 15
:1 were diagnostically equivalent to uncompressed images of uterine fi
broid tumors.