Mebenzadole was tested for in vivo effect on the eggs of B. transfuga
recovered from polar bears treated with the drug. A marked reduction o
f the number of eggs that developed to the larval stage was observed.
The pre-treatment percentage of incubated eggs that developed to the l
arval stage was 80 %-92 %. On day 1, after treatment was starting, the
percentage was 26 %-70 %, on day 2 the number was 0 %-9 % and on day
3 it was 0 %-1 %. No eggs developed on day 4 and thereafter. Coprologi
cal examinations were negative after 4-7 days the treatment was starti
ng.