CELLULAR-DISTRIBUTION OF CALBINDIN D-28K MESSENGER-RNAS IN THE ADULT-MOUSE BRAIN

We have determined the cellular distribution of calbindin D-28K mRNAs throughout the mouse brain by in situ hybridization. While these studi es identified neuronal populations similar to those previously identif ied in rat brain by immunohistochemistry, some discrepancies exist. Th ese may derive from species differences or from the immunological cros s-reactivity of calbindin D-28K antiserum with other proteins. We note an intriguing association between the distribution of neurons contain ing calbindin D-28K mRNA and those reported by others to contain the i nositol 1,4,5-triphosphate (InsP(3)) receptor. (C) 1994 Wiley-Liss, In c.