RELATIONSHIP BETWEEN EXERCISE TOLERANCE, HEMODYNAMICS AT REST AND DURING EXERCISE AND EJECTION FRACTION, AND THEIR PROGNOSTIC RELEVANCE IN ASYMPTOMATIC POSTINFARCTION PATIENTS

Citation
K. Meyer et al., RELATIONSHIP BETWEEN EXERCISE TOLERANCE, HEMODYNAMICS AT REST AND DURING EXERCISE AND EJECTION FRACTION, AND THEIR PROGNOSTIC RELEVANCE IN ASYMPTOMATIC POSTINFARCTION PATIENTS, Cardiology, 84(1), 1994, pp. 33-41
Citations number
36
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
ISSN journal
00086312
Volume
84
Issue
1
Year of publication
1994
Pages
33 - 41
Database
ISI
SICI code
0008-6312(1994)84:1<33:RBETHA>2.0.ZU;2-6
Abstract
In 309 postmyocardial infarction patients (age 40 +/- 7.7 years) witho ut persistent ischemia there is only a weak correlation between ejecti on fraction (EF) and exercise tolerance (r = 0.45, p < 0.01), and betw een EF and maximum cardiac output (CO; 0.41, p < 0.01) and maximum pul monary capillary wedge pressure (PCWP; r = -0.32, p < 0.001). The same was true for exercise tolerance and maximum PCWP (r = -0.53, p < 0.00 1). A big scattering of individual values could be observed. Although we found a high positive correlation between maximum CO and exercise t olerance (r = 0.80, p < 0.001), in individual cases a low CO could be related to high exercise tolerance and vice versa. In the multivariate analysis, only the heart volume/kg body weight and maximum PCWP could be shown to be of independent prognostic importance for survival and/ or mortality in the following years (chi(2) = 5.9, p < 0.015 and chi(2 ) = 7.2, p < 0.007, respectively).