A CONVENIENT ALTERNATIVE ROUTE TO BETA-AMINOKETONES

Authors
SANMARTIN R DEMARIGORTA EM DOMINGUEZ E
Citation
R. Sanmartin et al., A CONVENIENT ALTERNATIVE ROUTE TO BETA-AMINOKETONES, Tetrahedron, 50(7), 1994, pp. 2255-2264
Citations number
42
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
7
Year of publication
1994
Pages
2255 - 2264
Database
ISI
SICI code
0040-4020(1994)50:7<2255:ACARTB>2.0.ZU;2-8
Abstract
Enaminones has been prepared and submitted to conjugate reduction with LAH and the system Al2O3/R(2)NH to give beta-aminoketones. The latter tandem amination system has also been applied in the Mannich reaction , improving the synthesis of several new diaryl beta-aminoketones. Bes ides, the sequential use of DMFDMA and LAH-CuI on deoxybenzoins furnis hes a new route for the synthesis of enones.