THE PUBERTAL SPURT - EFFECTS OF SEX STEROIDS ON GROWTH-HORMONE AND INSULIN-LIKE GROWTH-FACTOR-I

Authors
CAUFRIEZ A
Citation
A. Caufriez, THE PUBERTAL SPURT - EFFECTS OF SEX STEROIDS ON GROWTH-HORMONE AND INSULIN-LIKE GROWTH-FACTOR-I, European journal of obstetrics, gynecology, and reproductive biology, 71(2), 1997, pp. 215-217
Citations number
34
Categorie Soggetti
Reproductive Biology","Obsetric & Gynecology
Journal title
European journal of obstetrics, gynecology, and reproductive biology → ACNP
ISSN journal
03012115
Volume
71
Issue
2
Year of publication
1997
Pages
215 - 217
Database
ISI
SICI code
0301-2115(1997)71:2<215:TPS-EO>2.0.ZU;2-R
Abstract
In puberty, the growth spurt and the appearance of secondary sex chara cteristics occur concomitantly with an increase of sex steroids, growt h hormone (GH) and insulin-like growth factor I (IGF-I). A number of e xperiments indicate that sex steroids exert a stimulatory action on th e somatotropic axis. This effect is due to an amplifying action of oes tradiol (secreted by the ovaries dr after testosterone aromatization) on the neuroendocrine regulation of pulsatile GH release. (C) 1997 Els evier Science Ireland Ltd.