J. Ohanlon et Kw. Harper, EPISTAXIS AND NASOTRACHEAL INTUBATION - PREVENTION WITH VASOCONSTRICTOR SPRAY, Irish journal of medical science, 163(2), 1994, pp. 58-60
Eighty patients having anaesthesia for oral surgery requiring nasal in
tubation were randomly allocated to be intubated with either a plain M
agill red rubber or cuffed polyethylene endotracheal tube and in a dou
ble blind manner, to receive xylometazoline 0.1% vasoconstrictor nasal
spray. The extent of any epistaxis occurring was assessed by an indep
endent observer. With the Magill tube there was bleeding in one out of
twenty patients in both the vasoconstrictor group and non vasoconstri
ctor group at intubation and no bleeding in either of the two groups a
t extubation. With the polyethylene tube sixteen out of twenty patient
s had bleeding in the non vasoconstrictor group. This improved to seve
n out of twenty with the administration of vasoconstrictor drops at in
tubation (chi square 10.2; p<0.01) in the polyethylene tube group. At
extubation ten out of twenty patients had bleeding in the non vasocons
trictor group improving to two out of twenty with the administration o
f the vasoconstrictor (chi square 9.6; p,0.01). The use of the vasocon
strictor xylometazoline helped to reduce epistaxis that occurred durin
g nasal intubation and further study into the type of endotracheal tub
e is recommended.