Kallmann syndrome is a rare combination of hypogonadotropic hypogonadi
sm due to hypothalamic insufficiency and anosmia. In both patients tre
ated at our institution for infertility, a malformation of the uterus
was noted: one patient had a unicornuate uterus, the other a uterus wi
th a fundal hypoplasia and tubes of approximately 9 cm. It is not clea
r if the malformation is in association with Kallmann syndrome or pure
ly coincidental. Given the known association of other malformations wi
th Kallnann syndrome, we suppose that probably an underlying genetic d
efect having to do with organogenesis is the cause of the uterine malf
ormations.