KALLMANN SYNDROME AND ASSOCIATED MALFORMATION OF THE UTERUS

Citation
Aw. Brandenberger et al., KALLMANN SYNDROME AND ASSOCIATED MALFORMATION OF THE UTERUS, Fertility and sterility, 61(2), 1994, pp. 395-397
Citations number
6
Categorie Soggetti
Obsetric & Gynecology
Journal title
ISSN journal
00150282
Volume
61
Issue
2
Year of publication
1994
Pages
395 - 397
Database
ISI
SICI code
0015-0282(1994)61:2<395:KSAAMO>2.0.ZU;2-B
Abstract
Kallmann syndrome is a rare combination of hypogonadotropic hypogonadi sm due to hypothalamic insufficiency and anosmia. In both patients tre ated at our institution for infertility, a malformation of the uterus was noted: one patient had a unicornuate uterus, the other a uterus wi th a fundal hypoplasia and tubes of approximately 9 cm. It is not clea r if the malformation is in association with Kallmann syndrome or pure ly coincidental. Given the known association of other malformations wi th Kallnann syndrome, we suppose that probably an underlying genetic d efect having to do with organogenesis is the cause of the uterine malf ormations.